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For people with eye problems: This drug may cause sudden loss of vision in one or both eyes. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. How it works Sildenafil belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. Drinking alcohol with this medicine can cause side effects. I am only 29 years old, married to a very wonderful and attractive man, but honestly I could care less about sex. In this study, researchers looked at the effects of treating ED with Viagra in a carefully selected group of 35 men with mild to moderate heart failure who did not use nitates.

There are possible side effects with Viagra and it is not a bad idea to think twice about taking it. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. Safety and effectiveness have not been established in pediatric patients.

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I was until I found out they probably were doing me no good. Figure 3: Mean Standing Systolic Blood Pressure Change from Baseline Blood pressure was measured after administration of VIAGRA at the same times as those specified for the first doxazosin study. The incidents include abnormal heart rhythm (atrial fibrillation and ventricular arrhythmia), low blood pressure, myocardial infarction, and blood clots (thromboembolism). Hepatic Impairment In volunteers with hepatic impairment (Child-Pugh Class A and B), sildenafil clearance was reduced, resulting in higher plasma exposure of sildenafil (47% for C max and 85% for AUC). The pharmacokinetics of sildenafil are dose-proportional over the recommended dose range.

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For the 19 subjects who received both VIAGRA and matching placebo, the placebo-subtracted mean maximum decreases from baseline (95% CI) in systolic blood pressure were as follows: The mean profiles of the change from baseline in standing systolic blood pressure in subjects treated with doxazosin in combination with 50 mg VIAGRA or matching placebo are shown in Figure 3. You may take it up to 4 hours before sexual activity. For more information, please consult with your healthcare provider. Viagra was even posted over home base when Pfizer was the primary sponsor of pro baseball. In Vivo Studies No significant interactions were shown with tolbutamide (250 mg) or warfarin (40 mg), both of which are metabolized by CYP2C9.

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Data from subjects exposed to high systemic levels of sildenafil are limited. If Viagra is consumed alongside a meal with a high-fat content, it will take much longer for the medication to work. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. VIAGRA connect is also available from many registered UK pharmacy chains and independent pharmacies. Sildenafil was not carcinogenic when administered to mice for 18-21 months at dosages up to the Maximum Tolerated Dose (MTD) of 10 mg/kg/day, approximately 0. But, Viagra use in individuals without erectile dysfunction does not seem to have any effect.