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They were, in fact, working on a drug for hypertension, or high blood pressure, and angina pectoris, a symptom of ischemic heart disease. Both sildenafil and the metabolite have terminal half lives of about 4 hours. Because of this, male pilots are not allowed to take Viagra within six hours of a flight. If your husband has been experiencing difficulty sleeping, you may want to consult with the physician to determine the underlying cause and possible treatment options, if necessary. After the patent expires, generic companies are allowed to request permission to have the "recipe." Currently, there is no generic for Viagra in the U. Through meds and seeing a psychologist to get to the root of the problem which was a loss at the age of nine (my dad), I am now able to control the hyperventilation, racing heart, etc.

Taking sildenafil with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack. This is not a complete list of side effects and others may occur. It’s also the hormone most closely linked to male sexuality, and it’s responsible for the development of sexual organs and sperm. Alpha-blockers Use caution when co-administering alpha-blockers with VIAGRA because of potential additive blood pressure-lowering effects.

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Goldenberg MM "Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction." Clin Ther 20 (1998): 1033-48 8. What should I do if I’ve taken more than 1 tablet by mistake? The maximum dosage is 100 mg, therefore, you would not want to increase beyond this dosage. Hemic and Lymphatic: vaso-occlusive crisis: In a small, prematurely terminated study of REVATIO (sildenafil) in patients with pulmonary arterial hypertension (PAH) secondary to sickle cell disease, vaso-occlusive crises requiring hospitalization were more commonly reported in patients who received sildenafil than in those randomized to placebo.

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The AUC of the active metabolite, N-desmethyl sildenafil, was increased 62% by loop and potassium-sparing diuretics and 102% by nonspecific beta-blockers. The cause is usually related to a decrease in the blood supply to the penis as well as to injury to the nerves that are responsible for the erection mechanism.

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By inhibiting phosphodiesterase, Viagra enhances the effect of nitric oxide allowing for smooth muscle relaxation and increasing blood flow to specific areas of the body in the presence of sexual arousal or stimulation. You would want to discuss with your doctor what class of antihypertensive medication you are taking, what dose, and what the possible risks might be. Viagra should be used with caution in patients with heart disease, including arrhythmias (abnormal heart rhythms); a recent history (in the past 6 months) of a heart attack, stroke, or heart rhythm disorder; congestive heart failure; high or low blood pressure; and coronary artery disease. If you have these symptoms, stop taking VIAGRA and contact a doctor right away. He aslo has a problem keeping an erection and we both think that he needs Viagra or something??? One or two glasses of wine or beer shouldn’t have too much of a detrimental effect, although results will vary from person to person. But if you remember just a few hours before your next scheduled dose, take only one dose.