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One concern is if you take nitroglycerin for angina. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. Also the medication is recommended to be used with caution by patients who have had life-threatening arrhythmias, heart attack, or stroke within the last six months, cardiac failure, coronary artery disease resulting in unstable angina, or by patients with left ventricular outflow obstruction.

Dilantin could increase the metabolism of sildenafil. Osol pointed out that "this is an important distinction, because it demonstrates a selective effect of Viagra on the uteroplacental circulation and avoids some of the complications of antihypertensive therapy during pregnancy, particularly the danger of reducing uteroplacental blood flow (placental underperfusion) secondary to the reduction of systemic blood pressure." Hypertensive pregnancy develops in about 10 percent of women, disrupting normal vascular adaptation.

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In addition, in most cases the problem for women is not with physical arousal but rather a lack of sexual desire. One randomized, double-blind, placebo-controlled, crossover, flexible-dose (up to 100 mg) study of patients with erectile dysfunction resulting from spinal cord injury (n=178) was conducted. This is because the fat in your digestive system causes the medication to enter your blood more slowly.

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McLeod AL, McKenna CJ, Northridge DB "Myocardial infarction following the combined recreational use of Viagra and cannabis." Clin Cardiol 25 (2002): 133-4 17. In the nonpregnant rat the AUC at this dose was about 20 times human AUC.

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Nitric oxide allows the smooth muscles inside the penis to relax, promoting more blood flow to the area during sexual arousal or stimulation. Furthermore, it was only possible that this side effect was related to treatment and a causal relationship to Viagra was uncertain. It is not possible to determine whether these events were directly related to Viagra. All you have to pay is shipping costs and you will receive a free Viagra ED trial pack. Read More Hi, I was just wondering have their been any studies done on the side effect of Viagra? Read More I get a tingle or pressure outside the skull as opposed to a headache, I definetely have anxiety, I went through a strange order where I was overstimulated on viagra and had to go to the ER. Before starting the study, the women reported a variety of sexual problems, including lack of libido, difficulty becoming aroused or becoming lubricated, lack of orgasm, or delay in achieving orgasm. Some people may also have ringing in their ears (tinnitus) or dizziness. Effects On Bleeding There have been postmarketing reports of bleeding events in patients who have taken VIAGRA. Kloner RA, Zusman RM "Cardiovascular effects of sildenafil citrate and recommendations for its use." Am J Cardiol 84 (1999): n11-7 21.