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If you take too much: You could have dangerous levels of the drug in your body. Renal Impairment No dose adjustment is required for mild (CLcr=50-80 mL/min) and moderate (CLcr=30-49 mL/min) renal impairment. Viagra’s effects typically last for between four and six hours, and it should not be taken unless you intend to have sex. Visit MedWatch or call 1-800-FDA-1088. *Eligibility required.

In fixed-dose studies, the incidence of some adverse reactions increased with dose. In some patients, concomitant use of these two drug classes can lower blood pressure significantly [see DRUG INTERACTIONS and CLINICAL PHARMACOLOGY] leading to symptomatic hypotension (e.g., dizziness, lightheadedness, fainting). According to the prescribing information, some of the possible side effects associated with Viagra treatment include headache, flushing, dyspepsia (upset stomach, indigestion), nasal congestion, urinary tract infections, abnormal vision, diarrhea, dizziness and rash.

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An E-box sequence within this 69-bp fragment is necessary for high-level expression, but not for rhythmic expression, indicating that PER mediates circadian transcription through other sequences in this fragment. All three of these medications inhibit an enzyme (PDE-5) that breaks down the substance produced by the penile tissue in response to sexual stimulation, and helps the erection occur.

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The usual dosage for Revatio is 20 mg administered three times daily. Levitra (vardenafil) is similar to Viagra (sildenafil), in that it lasts about five hours; Viagra (sildenafil) lasts about four hours. Dosage Adjustments Due To Drug Interactions Ritonavir The recommended dose for ritonavir-treated patients is 25 mg prior to sexual activity and the recommended maximum dose is 25 mg within a 48 hour period because concomitant administration increased the blood levels of sildenafil by 11-fold [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. Medications for hypertension (high blood pressure) are usually fine to take with it, as far as drug interactions go. HOW SUPPLIED Dosage Forms And Strengths VIAGRA is supplied as blue, film-coated, rounded-diamond-shaped tablets containing sildenafil citrate equivalent to 25 mg, 50 mg, or 100 mg of sildenafil.

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Grapefruit and grapefruit juice should be avoided, as enzymes in the fruit can stop Viagra from working altogether. In placebo-controlled clinical studies, the discontinuation rate due to adverse reactions for VIAGRA (2. A particular concern is severe hypotension observed when flibanserin is taken with alcohol. Viagra begins to exert its therapeutic effect within one hour with the duration of effects lasting for up to four hours. Patients should always ask their doctors for medical advice about adverse events. The study started in 2015 and involved 11 hospitals.