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The medication was first developed in England for used as an blood pressure reducer, but it worked better for penile dysfunction, so the makers decided to market it for that. Is it safe and does it affect chances of getting pregnant? Michelle McDermott, PharmD Q: Where can one buy generic Viagra? When getting a prescription from a doctor, you may want to ask that they write the prescription for a higher dose and have you cut it, to avoid confusion. There were four subjects with a decrease from baseline in standing systolic BP > 30 mmHg following VIAGRA 100 mg, one subject with a decrease from baseline in standing systolic BP > 30 mmHg following placebo and one subject with a decrease from baseline in standing systolic BP > 30 mmHg following both VIAGRA and placebo.

I am worried because my husband still feels he can take the Viagra. If Viagra Connect is not right for you, there are a number of other impotence medications. Patients should always ask their doctors for medical advice about adverse events.

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In those patients already taking an optimized dose of a PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose. Less common Viagra side effects include dizziness, increased frequency of urination, indigestion, pain on urination, and stomach upset. Have any of your heart medications been increased, especially ones that are known to cause erectile dysfunction, such as the beta blocker family, Tenormin (atenolol), Lopressor (metoprolol) and others? S. research centers between September 2003 and January 2007.

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There have been some patients that have built a tolerance to this medication and have found that even though they were able to get an erection before utilizing it, they no longer are able to do so without the assistance of the ED medication. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking.

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A: Erectile dysfunction is a common problem in diabetic men. Sildenafil at recommended doses has no effect in the absence of sexual stimulation. Could Viagra have this effect and if so, when should he take it? While the precise biological actions of sildenafil in the heart are not fully understood, the drug is known to work by stopping the action of an enzyme, called phosphodiesterase 5 (PDE5A), the researcher says.  This enzyme is involved in the breakdown of a key molecule, cyclic GMP, which helps control stresses and limit overgrowth in the heart.  PDE5A is also the biological pathway blocked in the penis by sildenafil to promote the relaxation of blood vessels and maintain erections.  Funding for this study was provided by the National Institutes of Health (NIH), the Peter Belfer Laboratory Foundation and the Bernard Family Foundation.  The makers of the drug had no involvement in the design or support of the research. Because of these possible events, the patients should be monitored closely.