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Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Carcinogenesis Sildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting in total systemic drug exposure (AUCs) for unbound sildenafil and its major metabolite of 29-and 42-times, for male and female rats, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 100 mg. This could lead to decreased effects of the sildenafil.

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There was one subject with a decrease from baseline in standing systolic BP > 30mmHg following VIAGRA 50 mg and one subject with a decrease from baseline in standing systolic BP > 30 mmHg following both VIAGRA 50 mg and placebo. Other medications that are in the same family and work in a similar manner are Cialis (tadalafil) and Levitra (vardenafil), but if one does not work as well for you anymore, another may work better. If you have liver or kidney problems, Viagra’s effects could last for longer, although it might not be safe to take Viagra with these conditions. Sex drive is quite complex: There’s both a physical and a psychological component. Michelle McDermott, PharmD Q: Where can one buy generic Viagra?

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A: Viagra (sildenafil) works by inhibiting the chemical phosphodiesterase, which leads to an increase in the effect of nitric oxide. Most importantly, you should talk about the drug, your medical history and your concerns with your doctor. For more information, ask your healthcare provider or pharmacist. The side effects included headaches, dizziness and just being tired.

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Patti Brown, PharmD Q: My husband is recovering from prostate cancer surgery and was told to take one-half of a Viagra pill every other day to increase blood flow. Another thing to consider is that sexual activity is associated with a degree of cardiac risk. Conversely, flibanserin works to raise levels of dopamine and norepinephrine to promote desire and arousal. In addition, in most cases the problem for women is not with physical arousal but rather a lack of sexual desire. It said the investigators at the AMC had confirmed a non-Pfizer manufactured generic version of sildenafil was used, but that no clinical trial participants were administered Viagra, Pfizer sildenafil or any other Pfizer medicine. "Viagra is indicated for the treatment of the symptoms of erectile dysfunction in adult men (aged 18 years and over)," the Pfizer statement said. "The safety and efficacy of Viagra has been well documented in clinical studies involving more than 15,000 patients. "We wish to express our sympathy for the trial participants and their families.Viagra Side Effects By Andrew Kline MD Medical Consultant June 14, 2012 Very few drugs work perfectly and there is no difference with Viagra, and any medication can have side effects.