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It works by boosting the effects of nitric oxide, relaxing the smooth muscles of the arteries in the penis, allowing for increased blood flow and resulting in an erection. However, according to the prescribing information, Viagra may be taken anywhere within a range from 30 minutes to four hours prior to sexual activity. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat.

Whether or not Viagra is safe for you will depend on the reason for your heart valve replacement. Viagra overdose A Viagra overdose can be serious. When VIAGRA is co-administered with an alpha-blocker, patients should be stable on alpha-blocker therapy prior to initiating VIAGRA treatment and VIAGRA should be initiated at 25 mg [see WARNINGS AND PRECAUTIONS, DRUG INTERACTIONS, and CLINICAL PHARMACOLOGY]. The combination of medications can cause a serious drop in blood pressure. Vobig MA "Retinal side-effects of sildenafil." Lancet 353 (1999): 1442 40. Effects of VIAGRA on Blood Pressure Single oral doses of sildenafil (100 mg) administered to healthy volunteers produced decreases in sitting blood pressure (mean maximum decrease in systolic/diastolic blood pressure of 8.

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Grapefruit and grapefruit juice may interact with sildenafil and lead to unwanted side effects. Having a large, high-in-fat meal just before you take your Viagra can make it take longer to start working. You can also find helpful information on erectile dysfunction at //www.everydayhealth.com/erectile-dysfunction/guide/. She also noted how it underscores the sexual ambivalence present in our society—our obsession and disgust with sex.

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At 24 hours the plasma levels of sildenafil were still approximately 200 ng/mL, compared to approximately 5 ng/mL when sildenafil was dosed alone. Do not use VIAGRA for a condition for which it was not prescribed.

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Thus, the activities of E2F, a family of transcription factors involved in cell proliferation, are regulated by at least two types of cell growth regulators: the retinoblastoma protein family and the cyclin-dependent kinase family. Paused   You're listening to a sample of the Audible audio edition. Boolell M, Gepi-Attee S, Gingell JC, Allen MJ "Sildenafil, a novel effective oral therapy for male erectile dysfunction." Br J Urol 78 (1996): 257-61 34. You also may want to try Cialis (tadalafil) or Levitra (vardenafil) if your physician feels it may help better. Based on effectiveness and toleration, the dose may be increased to a maximum recommended dose of 100 mg or decreased to 25 mg. Also the medication is recommended to be used with caution by patients who have had life-threatening arrhythmias, heart attack, or stroke within the last six months, cardiac failure, coronary artery disease resulting in unstable angina, or by patients with left ventricular outflow obstruction. While this normally would be expected to be of little consequence in most patients, prior to prescribing VIAGRA, physicians should carefully consider whether their patients with underlying cardiovascular disease could be affected adversely by such vasodilatory effects, especially in combination with sexual activity. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat.