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Clinical Pharmacology CLINICAL PHARMACOLOGY Mechanism Of Action The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation. The use of Viagra-like drugs in women is not as straightforward, and a similar treatment does not exist for women. If you have an erection that lasts more than 4 hours, get medical help right away.

In addition to the active ingredient, sildenafil citrate, each tablet contains the following inactive ingredients: microcrystalline cellulose, anhydrous dibasic calcium phosphate, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, triacetin, and FD & C Blue #2 aluminum lake. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.   Based on these studies, the most common side effects of Viagra (occurring in more than 2 percent of people) include:   Headaches --in up to 16 percent of people Facial flushing -- up to 10 percent Indigestion, known as dyspepsia -- up to 7 percent  Nasal congestion -- up to 4 percent Urinary tract infections (UTI) -- up to 3 percent Vision problems, including trouble telling the difference between blue and green, increased sensitivity to light, or blurred vision -- up to 3 percent Diarrhea -- up to 3 percent Dizziness -- up to 2 percent Unexplained rash -- up to 2 percent.   There were some other common side effects (also seen in more than 2 percent of people) that were just as common in people taking a sugar pill instead of Viagra as they were in people taking the actual drug. Other blood pressure medications reduce blood pressure, but not in the same sudden type of reaction. A: Viagra (sildenafil) and the other drugs for erectile dysfunction, such as Levitra (vardenafil) and Cialis (tadalafil), work by inhibiting the chemical phosphodiesterase, which leads to an increase in the effect of nitric oxide.

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Most medications can be cut in two if they are not extended release, but you should always check with your doctor or pharmacist, as the guideline is not always true. Sildenafil slows down the progression of your illness. Stop taking VIAGRA and call your healthcare provider right away if you have any sudden vision loss sudden hearing decrease or hearing loss. Renal dialysis is not expected to accelerate clearance as sildenafil is highly bound to plasma proteins and it is not eliminated in the urine. Certains hommes ne parviennent pas toujours a surmonter ce problème par honte et souvent n'osent pas en parler que ce soit a leur médecin ou encore a leur partenaire. Read More Vietnam, Hep C was unknown then so I was treated for Hep B and believed cured until I started developing various side effects due to Hep C around 2000.

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However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. The patent on Viagra is supposed to expire in March 2012 in the United States according to the United States Patent and Trademark Office. Its mode of action as far as it relates to FSIAD isn’t well understood.

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Sources say consuming a lot of alcohol over time can cause shrinkage in your testicles. It should be taken 30 minutes to an hour before it is needed, but can be taken up to 4 hours before it is needed. You also may want to try Cialis (tadalafil) or Levitra (vardenafil) if your physician feels it may help better. VIAGRA connect is also available from many registered UK pharmacy chains and independent pharmacies. Through this action, the drugs work to fix a functional problem. Also talk with your doctor if you have a low or high resting blood pressure, or a history of heart failure or coronary artery disease.


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