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Once you've swallowed one pill, it may take up to 60 minutes to take full effect and this may last for up to 4 hours. The pharmacokinetics of sildenafil in patients with severely impaired hepatic function (Child-Pugh Class C) have not been studied. Safety and effectiveness have not been established in pediatric patients.

Do not take Viagra (sildenafil) if you are also using a nitrate drug for chest pain or heart problems. Avoid using any other medicines to treat impotence, such as alprostadil or yohimbine, without first talking to your doctor.

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Nitric oxide also opens the blood vessels throughout the body, which can cause decreased blood pressure. Read More April 1, 2010 (Nuthetal, Germany) — The largest observational study so far to examine the association between chocolate consumption and risk of cardiovascular disease has found that those who ate the most chocolate--around 7.

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Viagra, commonly referred to as the "little blue pill" was the first erectile dysfunction medication to be approved by the U. Conti CR, Pepine CJ, Sweeney M "Efficacy and safety of sildenafil citrate in the treatment of erectile dysfunction in patients with ischemic heart disease." Am J Cardiol 83 (1999): c29-34 7. All you have to pay is shipping costs and you will receive a free Viagra ED trial pack.

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It’s also the hormone most closely linked to male sexuality, and it’s responsible for the development of sexual organs and sperm. When sexual stimulation causes local release of NO, inhibition of PDE5 by sildenafil causes increased levels of cGMP in the corpus cavernosum, resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Cardiovascular, side effects viagra and alcohol side effects and even the preliminary results. If it is not treated right away, priapism can permanently damage your penis sudden vision loss in one or both eyes. A prolonged erection (priapism) can damage the penis. All of this is due to a combination of, among other things, changing demographics (e.g. aging population), direct to consumer advertising/consumer-based medicine (Viagra being one of the first drugs to be advertised directly to the consumer) and pharmaceutical expansion.