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CONTRAINDICATIONS Nitrates Consistent with its known effects on the nitric oxide/cGMP pathway [see CLINICAL PHARMACOLOGY], VIAGRA was shown to potentiate the hypotensive effects of nitrates, and its administration to patients who are using nitric oxide donors such as organic nitrates or organic nitrites in any form either regularly and/or intermittently is therefore contraindicated. Increased side effects can include low blood pressure or erections that last longer than normal.
Drugs you should not use with sildenafil Do not take these drugs with sildenafil. William Gault, RPh Q: My husband is on blood pressure medications and tried Viagra.
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This does depend on the individual, but this is the case for most men. Sildenafil oral tablet is used to treat erectile dysfunction (ED). When sexual stimulation occurs, nitric oxide is released by the nervous system in the erectile tissue of the penis. Larger effects were recorded among patients receiving concomitant nitrates [see CONTRAINDICATIONS].
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Gilad R, Lampl Y, Eshel Y, Sadeh M "Tonic-clonic seizures in patients taking sildenafil." BMJ 325 (2002): 869 36. The major circulating metabolite results from N-desmethylation of sildenafil, and is itself further metabolized. Because of this, male pilots are not allowed to take Viagra within six hours of a flight. Viagra is currently only available in brand name version and there has not been a date set for the release of its generic. Rarely reported side effects include: an erection that will not go away (priapism). Read More This, in turn, affects the blood pressure and can possibly contribute to the development of an abnormal heart rate, a stroke or a heart attack.
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Even though this total dosage produced plasma sildenafil concentrations which were approximately 2 to 5 times higher than the mean maximum plasma concentrations following a single oral dose of 100 mg in healthy male volunteers, the hemodynamic response to exercise was preserved in these patients. There have been some patients that have built a tolerance to this medication and have found that even though they were able to get an erection before utilizing it, they no longer are able to do so without the assistance of the ED medication. Viagra's impact on men's sex lives also impacts women's sex lives. The Medicines & Healthcare products Regulatory Agency (MHRA) announced this form of Viagra without prescription in November 2017 for men over the age of 18 who have erectile dysfunction. You may report side effects to FDA at 1-800-FDA-1088. Be very cautious about purchasing a drug claiming to be the generic. Lori Poulin, PharmD Q: Can stroke survivors take Viagra? It improves the erectile response when a man is already sexually stimulated, but it does not provide sexual stimulation.
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