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Viagra was originally developed by Pfizer but is now off patent and available as a generic. In the rat pre-and postnatal development study, the no observed adverse effect dose was 30 mg/kg/day given for 36 days. Before you take VIAGRA, tell your healthcare provider if you: have or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve or heart failure have had heart surgery within the last 6 months have pulmonary hypertension have had a stroke have low blood pressure, or high blood pressure that is not controlled have a deformed penis shape have had an erection that lasted for more than 4 hours have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia have retinitis pigmentosa, a rare genetic (runs in families) eye disease have ever had severe vision loss, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) have bleeding problems have or have had stomach ulcers have liver problems have kidney problems or are having kidney dialysis have any other medical conditions Tell your healthcare provider about all the medicines you take*, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Please see full prescribing information for VIAGRA (25 mg, 50 mg, 100 mg) tablets. Co-administration of erythromycin, a moderate CYP3A4 inhibitor, resulted in a 160% and 182% increases in sildenafil Cmax and AUC, respectively. The Queensland trial is significantly different to the Dutch one, where Sildenafil is used in to promote growth in severely underdeveloped unborn babies.
With PAH, the blood pressure in your lungs is too high. Kimberly Hotz, PharmD Q: Is there a generic for Viagra? Taking Viagra with a nitrate medicine can cause a serious decrease in blood pressure, leading to fainting, stroke, or heart attack.
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A: Viagra (sildenafil) must be used with caution in patients taking an antihypertensive medication. For people with problems with the shape of their penis: If you have a problem with the shape of your penis, such as Peyronie’s disease, this drug raises your risk of having an erection that lasts more than 4 hours. How do I take VIAGRA connect for the best results? The most common side effects of flibanserin include: dizziness difficulty falling asleep or remaining asleep nausea dry mouth tiredness hypotension, or low blood pressure fainting or loss of consciousness You shouldn’t take flibanserin if you drink alcohol or have liver problems. The primary endpoint was time to limiting angina in the evaluable cohort.
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If you accidentally take too much VIAGRA, call your doctor or go to the nearest hospital emergency room right away. Excessive alcohol consumption combined with Viagra may cause light-headedness, dizziness, headaches, heart palpitations or fainting. Patti Brown, PharmD Q: Is it safe to take Viagra?
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The maximum recommended dose is 100 mg with a maximum recommended frequency of administration of once daily. A: Viagra (sildenafil) belongs to a class of medications, known as phosphodiesterase inhibitors, which are indicated for the treatment of erectile dysfunction in men. You would want to discuss with your doctor what class of antihypertensive medication you are taking, what dose, and what the possible risks might be. Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of VIAGRA without sexual activity. Viagra may help women who report having difficulties with lubrication because the increase in blood flow to the female genitals would subsequently increase lubrication. The dosage for Cialis for once daily use may be increased to 5 mg if necessary. Whilst alcohol can help to overcome anxiety, it can also affect sexual prowess. A: It costs pharmacies a lot of money to purchase brand-name drugs from wholesalers. Nonclinical Toxicology Carcinogenesis, Mutagenesis, Impairment Of Fertility Carcinogenesis Sildenafil was not carcinogenic when administered to rats for 24 months at a dose resulting in total systemic drug exposure (AUCs) for unbound sildenafil and its major metabolite of 29-and 42-times, for male and female rats, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 100 mg. No one dropped out of the study because of their side effects. In volunteers with severe (CLcr < 30 mL/min) renal impairment, sildenafil clearance was reduced, resulting in approximately doubling of AUC and Cmax compared to age-matched volunteers with no renal impairment [see DOSAGE AND ADMINISTRATION, and Use In Specific Populations].
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